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Elucidating the specific pharmacological mechanism of action (MOA) of In a natural way happening compounds can be hard. While Tarselli et al. (60) developed the main de novo synthetic pathway to conolidine and showcased that this naturally occurring compound correctly suppresses responses to both of… Read More
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Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors during the central nervous procedu… Read More
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